Olive oil, extra virgin
Anyone coming from the Mediterranean region of the world would tell you about
the health benefits, as well as the wonderful flavor, of a good dose of olive
oil on salads, pasta, fish and almost anything else. Fortunately, it is
available throughout the year to satisfy taste buds and promote good health.
Olive oil is made from the crushing and then subsequent pressing of olives. The
fact that olives are rich in oil is reflected in the botanical name of the olive
tree-Olea europea- since the word "oleum" means oil in Latin. Extra virgin olive
oil is derived from the first pressing of the olives and has the most delicate
flavor and most antioxidant benefits.
This chart graphically details the %DV that a serving of Olive oil, extra virgin
provides for each of the nutrients of which it is a good, very good, or
excellent source according to our Food Rating System. Additional information
about the amount of these nutrients provided by Olive oil, extra virgin can be
found in the Food Rating System Chart. A link that takes you to the In-Depth
Nutritional Profile for Olive oil, extra virgin, featuring information over 80
nutrients, can be found under the Food Rating System Chart.
Health Benefits
Description
History
How to Select and Store
How to Enjoy
Individual Concerns
Nutritional Profile
References
Health Benefits
Pure, extra virgin olive oil is not only a light and delicate addition to many
wonderful dishes, it is one of the most health-promoting types of oils
available. Olive oil is rich in monounsaturated fat, a type of fat that
researchers are discovering has excellent health benefits.
Protection Against Chronic Degenerative Disease
In many parts of the world, a high fat intake is associated with degenerative
diseases such as atherosclerosis, diabetes, asthma, colon cancer, and arthritis.
But in some parts of the world, a high fat intake is actually associated with
lower rates of these conditions. A closer look at the foods eaten in these
places reveals that the high fat intake is actually due to the generous use of
olive oil. Comparing these areas, such as the Mediterranean, where olive oil is
the main fat used, to other regions, like the United States, where other fats
such as animal fats, hydrogenated fats and vegetable oils like corn oil
dominate, turns up some very interesting data. It turns out that people who use
olive oil regularly, especially in place of other fats, have much lower rates of
heart disease, atherosclerosis, diabetes, colon cancer, and asthma.
Live Longer-Eat an Olive Oil-Rich Mediterranean-style Diet
In a prospective study (one in which participants are chosen and then followed
forward in time) involving 5,611 adults 60 years or older, adherence to a
Mediterranean style dietary pattern - characterized by high consumption of olive
oil, raw vegetables, soups, and poultry - was associated with a significantly
lower risk of death from all causes.
After 6.2 years, those most closely following a Mediterranean 'olive oil and
salad' dietary pattern had a 50% reduced risk of overall mortality. Much less
favorable were the results seen in those most closely following a 'pasta and
meat' dietary pattern - characterized by pasta, tomato sauce, red meat,
processed meat, added animal fat, white bread and wine - whose overall mortality
risk increased.
Study authors concluded, "Dietary recommendations aimed at the Italian elderly
population should support a dietary pattern characterized by a high consumption
of olive oil, raw vegetables and poultry." (Masala G, Ceroti M, et al., Br J
Nutr.)
Heart Health
Olive Oil Highly Protective against Heart Disease
Relying only on olive oil may cut your risk of coronary heart disease almost in
half, show results from the CARDIO2000 case-control study, published in Clinical
Cardiology (Kontogianni MD, Panagiotakos DB, et al.).
Conducted in Greece, and involving 700 men and 148 women with coronary heart
disease, and 1078 age- and sex-matched healthy controls, this study looked not
only at diet but also at alcohol intake, physical activity and smoking habits.
Nutritional habits, including use of oils in daily cooking or preparation of
food, was also evaluated.
Even after adjustments were made to account for a variety of other variables --
including body mass index, smoking, physical activity level, educational status,
a family history of heart disease, high blood pressure, high cholesterol and
diabetes -- exclusive use of olive oil was associated with a 47% lower
likelihood of having coronary heart disease.
Consuming other fats or oils as well as olive oil, however, conferred no
protection.
The researchers concluded, "Exclusive use of olive oil during food preparation
seems to offer significant protection against coronary heart disease,
irrespective of various clinical, lifestyle and other characteristics of the
participants."
Practical Tips:
Instead of serving butter, fill a small condiment dish with extra virgin olive
oil for use on bread, rolls, potatoes or other vegetables.
For even more flavor, try adding a few drops of balsamic vinegar or a
sprinkling of your favorite spices to the olive oil.
To get the most health benefit and flavor from your olive oil, buy and store
oil in opaque containers, and add olive oil to foods immediately after
cooking.
Studies on olive oil and atherosclerosis reveal that particles of LDL
cholesterol (the potentially harmful cholesterol) that contain the
monounsaturated fats of olive oil are less likely to become oxidized. Since only
oxidized cholesterol sticks to artery walls, eventually forming the plaques that
can lead to a heart attack or stroke, preventing the oxidation of cholesterol is
a good way to help prevent atherosclerosis. A recent in vitro study also showed
that polyphenolic compounds present in olive oil, including oleuropein, inhibit
the adhesion of monocyte cells to the blood vessel lining, a process that is
involved in the development of atherosclerosis. In addition, when people with
high cholesterol levels removed the saturated fat from their diets and replaced
it with olive oil, their total cholesterol levels dropped an average of 13.4%,
and their LDL cholesterol levels dropped by 18%. Note, however, that these
benefits occurred when they used olive oil in place of other fats, rather than
simply adding olive oil to a diet high in unhealthy fats.
A study published in the Medical Science Monitor reported that 2 tablespoons a
day of olive oil added to an otherwise unchanged diet in 28 outpatients, ranging
in age from 64 to 71, resulted in significant drops in total- and LDL
cholesterol. Mean concentrations of total cholesterol were lowered by 0.818
mmol/L, and mean concentrations of LDL dropped 0.782 mmol/L. Plus, subjects
ratio of HDL:LDL greatly improved; they ended up with higher amounts of
protective HDL in relation to lower amounts of dangerous LDL cholesterol.
Three other recent studies (Valavanidis et al.; Morella et al.; Masella et al.,
see references below) suggest that such heart-healthy effects from olive oil are
due not only to its high content of monounsaturated fats, but also to its hefty
concentration of antioxidants, including chlorophyll, carotenoids and the
polyphenolic compounds tyrosol, hydrotyrosol and oleuropein-all of which not
only have free radical scavenging abilities, but protect the vitamin E
(alpha-tocopherol) also found in olive oil.
Greek scientists at the University of Athens reporting their research in the
Journal of Agriculture and Food Chemistry believe the synergy of all these
beneficial nutrients is what is responsible for olive oil's contribution to the
health benefits of the Mediterranean diet, a hypothesis supported by Italian
research published in the Journal of Nutrition.
In this study, scientists found that the phenols in olive oil have very potent
antioxidant effects. The protective effects exerted by extra virgin olive oil
biophenols, namely, protocatechuic acid and oleuropein, against LDL oxidation
included:
completely preventing LDL's oxidation when placed in a medium containing
macrophage-like cells (in the arteries, arteriosclerosis begins when
macrophages damage LDL, starting the development of foam cells that infiltrate
the lining of the artery and begin plaque formation)
inhibiting the production of two powerful oxidants that would normally have
been produced and would have damaged LDL, thus preventing the expected
decrease in glutathione, a powerful antioxidant the body produces to disarm
oxidants (also called free radicals)
restoring to normal levels the protective activities of two free
radical-disarming enzymes that contain glutathione: glutathione reductase and
glutathione peroxidase
inducing higher than normal production and activity of both of these
glutathione-containing enzymes.
Olive Oil, Super Food for the Heart
A review of the research by noted olive oil researcher Maria Covas strongly
suggests that diets in which olive oil is the main source of fat can be a useful
tool against a wide variety of risk factors for cardiovascular disease. (Covas
MI, Pharmacology Research)
On November 2004, the Federal Drug Administration (FDA) of the U.S.A permitted a
claim on olive oil labels concerning: "the benefits on the risk of coronary
heart disease of eating about two tablespoons (23 g) of olive oil daily, due to
the monounsaturated fat (MUFA) in olive oil."
But recent studies have shown that olive oil contains much more than MUFA. Olive
oil is a functional food that is also rich in antioxidants and phenolic
compounds with a variety of protective effects.
The cholesterol of a person whose diet is high in olive oil will primarily
contain oleic acid, the fatty acid that predominates in olive oil, and oleic
acid is more resistant to free radical or oxidative damage. And not only will
the LDL of a person whose dietary fat is primarily olive oil produce LDL that is
more resistant to free radical damage, but that individual's LDL will be further
protected by olive oil's supplies of vitamin E and phenols with antioxidant
activity, further lessening the likelihood of its being oxidized.
By reducing both inflammation and free radical damage to cholesterol, dietary
olive oil protects the endothelium, the lining of our blood vessels, helping to
maintain its ability to relax and dilate (thus preventing high blood pressure).
By protecting LDL against oxidation, olive oil short circuits the process
through which atherosclerotic plaques form. (Only once oxidized does LDL adhere
to the endothelium, attracting immune cells (monocytes) that try to clear it
out, turn into foam cells and begin plaque formation.)
The anti-inflammatory effects of a virgin olive oil-rich diet also result in a
vascular environment in which platelets are less likely to clump together and
form blood clots. Not only do olive oil's antioxidant compounds lessen the
inflammation initiated by free radical damage, but olive oil is rich in
inhibitors of a compound called platelet activating factor (PAF). PAF begins the
clotting process by causing platelets to aggregate and is also involved in the
activation of immune cells and their binding to the endothelial wall.
Compared to diets high in saturated fat and low fat, high carbohydrate diets, a
number of studies have shown that olive oil-rich diets not only reduce LDL
cholesterol levels, but also lower blood sugar levels and decrease insulin
requirements in persons with type 2 diabetes.
Practical Tip: Rely on delicious, flavorful virgin olive oil as your first
choice for dressing salads. Put a little olive oil and balsamic vinegar on your
bread plate and use it to add flavor to crusty whole wheat bread and rolls.
Drizzle olive oil over potatoes, beans, grains, steamed vegetables, and soups.
You will not only enhance the flavor of your food, but greatly reduce your
cardiovascular disease risk.
Virgin Olive Oil the Best Oil for Heart Health
Virgin olive oil, a much richer source of polyphenols than refined olive or
other refined oils, is the best vegetable oil for heart health, shows the
results of the Eurolive study, published in the September 2006 Annals of
Internal Medicine.
The 6 research center study, led by Maria-Isabel Covas of the Municipal
Institute of Medical Research in Barcelona, assigned 200 healthy men from 5
European countries - Spain, Denmark, Finland, Italy and Germany - to one of
three sequences of daily consumption of olive oil. The men replaced their normal
dietary fats with olive oil (25 mL) containing either 2.7 (refined), 164
(virgin), or 366 (extra virgin) mg/kg of phenols for 3 weeks. This was followed
by 2 weeks without any olive oil and then a cross-over to each of the other 2
remaining interventions.
Blood samples were taken before and after each intervention to measure blood
sugar, total and HDL (good) cholesterol, triglycerides, free radical damage to
cholesterol, and antioxidant levels.
The data revealed a linear increase in HDL (good) cholesterol levels as the
phenolic content of the olive oil increased, with increases of 0.025, 0.032, and
0.045 mmol/L for the low, medium and high polyphenol-containing olive oils.
Oxidized LDL (the form in which LDL is involved in atherosclerosis) decreased
linearly, dropping from 1.21 U/L , to -1.48 U/L , to -3.21 U/L for the low-,
medium-, and high-polyphenol olive oil, respectively. And the ratio of total to
HDL cholesterol, considered the most specific cholesterol-associated risk factor
for cardiovascular disease, also decreased linearly as the phenolic content of
the olive oil rose.
"Olive oil is more than a monounsaturated fat. Its phenolic content can also
provide benefits for plasma lipid levels and oxidative damage," concluded the
researchers.
A statement released by the Municipal Institute of Medical Research noted, 'This
study represents a key piece for recommendations and contributes information
with great repercussions for the community, especially in populations or
countries where olive oil does not comprise the habitual oil of the diet."
Extra virgin olive oil-organic, if available-may cost a bit more than lesser
quality oils, but the significant increase in cardiovascular benefits, not to
mention richer flavor it provides, make it an extremely good investment in your
health.
Key to the Mediterranean Diet's Ability to Lower Blood Pressure
Theodora Psaltopoulou and colleagues from the University of Athens, Greece
investigated whether the Mediterranean diet as a whole, or just olive oil, is
responsible for the reduction in blood pressure associated with this way of
eating. Their finding: while the diet as a whole reduces blood pressure, olive
oil, by itself, is largely responsible.
The Greek team examined the ability of the total diet and of olive oil alone to
reduce arterial blood pressure. Their study included over 20,000 Greek
participants who were free of hypertension (high blood pressure) when the study
began. Food frequency questionnaires were completed and systolic and diastolic
blood pressures were taken.
Diet was evaluated by a 10 point score that reflected the extent to which study
participants followed the Mediterranean diet and also provided scores for
individual components of the diet, including olive oil.
Data analysis confirmed that the Mediterranean diet as a whole was significantly
associated with lower systolic and diastolic blood pressure as were olive oil,
vegetables and fruit. On the other hand, consumption of cereals, meat and meat
products, and alcohol intake was associated with higher blood pressure. When the
effects of olive oil and vegetables were compared, olive oil was found to be
responsible for the dominant beneficial effect on blood pressure.
Polyphenols, not Fats, Responsible for Olive Oil's Benefits
It's likely the abundance of polyphenols in extra virgin olive oil, rather than
its monounsaturated fatty acids, are responsible for its well-known
cardiovascular benefits.
And its rich supply of polyphenols, which are known to have anti-inflammatory,
antioxidant and anticoagulant actions, may also be central to emerging evidence
that olive oil's protective effects extend to colon cancer and osteoporosis (see
Protection against Colon Cancer, Olive Oil Polyphenols Prevent Bone Loss also in
this section).
Research conducted by Dr. Juan Ruano and colleagues at the Reina Sofia
University Hospital, Cordoba, Spain, and published in the Journal of the
American College of Cardiology, investigated the effects of virgin olive oil on
endothelial function in 21 volunteers with high cholesterol levels.
The endothelium, although just a one-cell thick layer of flat cells that lines
the inner wall of all blood vessels, may be the critical player in
cardiovascular health. Among its many functions, the endothelium orchestrates
the mechanics of blood flow, and regulates blood clot formation and the adhesion
of immune cells to the blood vessel wall (one of the first steps in the
formation of plaque).
Normally, after a meal, endothelial function is impaired for several hours.
Blood vessels become less elastic, and blood levels of free radicals potentially
harmful to cholesterol (lipoperoxides and 8-epi prostaglandin-F2) rise.
But when the subjects in this study ate a breakfast containing virgin olive oil
with its normal high phenolic content (400 ppm), their endothelial function
actually improved, blood levels of nitric oxide (a blood vessel-relaxing
compound produced by the endothelium) increased significantly, and far fewer
free radicals were present than would normally be seen after a meal.
When they ate the same breakfast containing the same type of virgin olive oil
with its phenolic content reduced to 80 ppm, the beneficial effects were
virtually absent, and concentrations of cholesterol-damaging free radicals
increased.
The results of this study underscore the importance of knowing how to select,
store and serve your olive oil to maximize its polyphenol content. For all the
information you need, see our How to Select and Store section below.
Olive Oil Especially Protective in People with High Cholesterol
A variation on the above study also shows that including some extra virgin olive
oil (which is rich in clot-fighting phenols) in your meals may help prevent the
formation of blood clots, an occurrence whose likelihood increases after eating,
particularly in people with high cholesterol.
In the early stages of atherosclerosis, the balance between clot-promoting and
clot-dissolving factors in the blood vessels shifts in favor of clot formation,
a situation made even more dangerous by the high levels of fat that can appear
in the blood after a meal.
Researchers had 21 people with high cholesterol eat two different breakfasts.
For one week, they consumed either white bread with virgin olive oil containing
400 parts per million phenols, or white bread with olive oil from which much of
the phenols had been extracted, leaving only 80 parts per million. Study
participants then switched to the opposite meal. After the high-phenol olive oil
meal, participants' concentrations of two clot promoters, factor VII antigen and
plasminogen activator inhibitor-1, were much lower compared to the low-phenol
olive oil meal. (Ruano J, Lopez-Miranda J, et al., Am J Clin Nutr.)
Olive Oil Cardio-Protective - But Don't Overdo It
It's the Mediterranean version of the French paradox: in the REGICOR Study,
conducted in Spain, researchers found a lower incidence of heart attacks despite
a high prevalence of risk factors for cardiovascular disease. Olive oil-which
accounts for nearly 35% of calories and is the main source of fat in
Mediterranean countries-was a likely explanation.
To investigate this, Maria-Isabel Covas, PhD, Head of The Research Group in
Oxidative Stress and Nutrition at the Lipids and Cardiovascular Epidemiology
Unit, Institute Municipal d́Investigació Mèdica, Barcelona, Spain, brought
together an international team with partners from Denmark, Finland, Germany and
Greece to collaborate in the EUROLIVE Project.
In addition to studies on the bioavailability of polyphenols from olive oil in
humans, the EUROLIVE Project has conducted 6 clinical trials in which 3 olive
oils, similar except for differences in their polyphenol content (low, 2.7
mg/kg; medium, 164 mg/kg; and high, 366 mg/kg), were given to healthy male
volunteers in intervention periods of 3 weeks at doses of 25 mL/day.
Results of the EUROLIVE studies have shown that:
The higher the polyphenolic content of the olive oil, the higher the increase in
levels of HDL "good" cholesterol. Average increase in HDL was 0.025 mmol/L for
low, 0.032 mmol/L for medium, and 0.045 mmol/L for high phenolic olive oil,
respectively. (Extra virgin olive oil contains the most polyphenols, followed by
virgin olive oil, olive oil and a highly refined olive oil called "pomace.")
Subjects' atherogenic index (their ratio of total cholesterol to HDL
cholesterol) and the oxidative (free radical) damage of cholesterol and other
lipids decreased as the polyphenolic content of the olive oil increased. (Lipid
oxidation--free radical damage to cholesterol and other fats-is considered a
high risk factor for coronary heart disease development.
In men from Northern and Central Europe who do not typically eat a Mediterranean
diet, daily consumption of 25 mL of olive oil resulted in a 3% decrease in
systolic blood pressure.
Consuming 25 mL/day of olive oil, in replacement of other fats, did not cause
weight gain.
A moderate amount of olive oil-a 25 mL dose (1.7 tablespoons)-did not promote
postprandial (after meals) oxidative stress (free radical damage to cholesterol)
whereas a single olive oil dose of 40 mL (2.7 tablespoons) did. Practical Tip:
Olive oil, particularly extra virgin olive oil, provides a number of
heart-healthy benefits-increasing HDL "good" cholesterol, improving the ratio of
LDL:HDL, and, if you aren't already following a Mediterranean diet, may lower
your systolic blood pressure as well. But don't overdo it. Consuming more than a
couple of tablespoons at a meal can increase free radical damage of cholesterol.
Key to the Mediterranean Diet's Ability to Reduce Breast Cancer Risk
Olive oil may be the key reason that eating a Mediterranean diet reduces breast
cancer risk, suggests a laboratory study published in the Annals of Oncology.
Oleic acid, the main monounsaturated fatty acid in olive oil, has been shown to
reduce the expression of the Her-2/neu oncogene, which is associated with the
aggressive growth of breast cancer tumors. High levels of Her-2/neu are found in
one-fifth of breast cancers, especially those that are resistant to treatment.
In this study, when Menendez and his colleagues from Northwestern University in
Chicago exposed two strains of aggressive breast cancer cells to oleic acid,
levels of Her-2/neu dropped 46%. When they combined oleic acid with lower levels
than are normally used of Herceptin, a drug used to treat breast cancer, oleic
acid greatly enhanced the effectiveness of the drug, dropping Her-2/neu
expression as much as 70%. The end result: oleic acid promoted the apoptotic
cell death (suicide) of aggressive, treatment resistant breast cancer cells.
A human study adds to the evidence that olive oil is a key factor in the
lowering of breast cancer risk associated with a Mediterranean diet. Results of
this two-year long study involving 755 women in the Canary Islands suggest that
monounsaturated fat and, specifically, olive oil exert a protective effect
against breast cancer.
Study participants consuming the most monounsaturated fat were found to have a
48% lower risk of breast cancer compared to women whose intake of
monounsaturated fat was lowest.
Among women consuming the most olive oil, specifically, the risk of breast
cancer was even lower. Compared to those consuming the least olive oil, women
whose daily intake of olive oil was at least 8.8 grams, the equivalent of just
.65 tablespoon/day, had a 73% lower risk of breast cancer risk!
Better Blood Sugar Control
Studies in diabetic patients have shown that healthy meals that contained some
olive oil had better effects on blood sugar even than healthy meals that were
low in fat. When olive oil is used to enhance a low-saturated fat, high
carbohydrate diabetic diet, the diet still has beneficial effects on blood sugar
control. In addition to this, a good diabetic diet with some olive oil added
helps to keep triglyceride levels low. Triglyceride levels tend to be high in
diabetic patients, which is a problem since high levels also contribute to the
development of heart disease. So a high carbohydrate, healthy diabetic diet with
some olive oil added in can help for several reasons.
Helps Prevent Belly Fat and Improve Insulin Sensitivity
What you eat may affect where fat deposits on your body. Belly fat is associated
with insulin resistance, which leads to further weight gain and increases risk
of type 2 diabetes.
When researchers fed type 2 diabetic patients different diets - a high
carbohydrate diet, or a diet rich in either saturated fat or olive oil
(Mediterranean diet) - the high carb diet increased abdominal fat compared to
the fat-rich diets. Of the three diets, the diet rich in olive oil did best,
preventing not only belly fat accumulation, but the insulin resistance and drop
in adiponectin seen after the high carbohydrate diet meals.
Adiponectin, a hormone produced and secreted by fat cells (adipocytes),
regulates sugar and fat metabolism, improves insulin sensitivity, and has
antiinflammatory effects on the cells lining the blood vessel walls. Low blood
levels of adiponectin are a marker for metabolic syndrome, are common in
obesity, and are also associated with increased heart attack risk.
Your diet supplies not just calories but information. The instructions delivered
to your cells by a Mediterranean-type diet rich in monounsaturated fat from
olive oil and nuts will improve your sensitivity to insulin, lower your blood
sugar, and help prevent fat from collecting around your middle. (Paniagua JA,
Gallego de la Sacristana A, et al., Diabetes Care)
Anti-Inflammatory Benefits
As far as other diseases go, regular use of olive oil has been associated with
lower rates of asthma and rheumatoid arthritis. The monounsaturated fats in
olive oil are used by the body to produce substances which are relatively
anti-inflammatory. By reducing inflammation, these fats can help reduce the
severity of arthritis symptoms, and may be able to prevent or reduce the
severity of asthma.
Minor components of extra virgin olive oil-namely, its squalene, beta-sitosterol
and tyrosol -may help explain why the Mediterranean diet has shown such
beneficial effects on cardiovascular health and cancer prevention, suggests a
study published in Free Radical Biology and Medicine. It is generally accepted
in the medical community that excessive production of free radicals and
inflammatory compounds derived from the body's use of omega-6 fatty acids (found
primarily in meats, corn, safflower and sunflower oils) contributes to the
development of both cardiovascular disease and cancer. In this study,
researchers tested the effects of squalene, beta-sitosterol and tyrosol on a
number of free radicals as well as on inflammatory compounds produced from
omega-6 fats (arachidonic acid metabolites). In each case, the olive oil
compounds either significantly inhibited production of the problem-causing
molecules or rendered them harmless.
Olive Oil Phenols' Help Prevent Bone Loss
The bone-sparing effects of olive polyphenols revealed in studies conducted by a
special team at INRA (France's National Institute for Agricultural Research) are
so dramatic that a new Belgian firm, BioActor, has licensed INRA's patents to
use olive polyphenols for osteoporosis prevention in food, supplements and
herbal medicines.
The World Health Organization calls osteoporosis its biggest global healthcare
problem with aging populations also beset by obesity, a condition now known to
greatly increase inflammation throughout the body, including in bones where it
significantly contributes to osteoporosis. Today, a woman's lifetime risk of
osteoporotic fracture is 30-40%, and even men face about a 13% risk.
INRA researchers, inspired by epidemiological evidence that people eating a
traditional Mediterranean diet were less likely to develop osteoporosis, began
investigating the effects of olive oil and different compounds in olive leaves
on bone metabolism.
Their early studies revealed that two olive polyphenols, oleuropin and
hydroxytyrosol, greatly lessen the inflammation-mediated bone loss involved in
osteoporosis.
Then they published research in the British Journal of Nutrition, showing that
both oleuropein and olive-oil feeding can prevent inflammation-induced
osteopenia (bone-thinning) in animals whose ovaries have been removed-an animal
model designed to simulate senile osteoporosis, the bone-wasting condition that
affects the elderly, as it combines both hormone deficiency with chronic
inflammation.
Although the animals did not fully recover all their bone density compared to
controls, those rats fed oleuropin (0.15g/kg) or olive-oil (50 g/kg) daily for 3
months recovered 70-75% of their bone density-a 50% improvement compared to
control animals, which were given 25g/kg peanut oil and 25 g/kg rapeseed oil
daily.
The INRA team, led by Dr. Veronique Coxam, is developing the protocol for a
human study, which, if all goes well, could be started before the end of 2006.
Olive Oil Phenols Protect DNA from Free Radical Damage
Extra-virgin olive oil, which, when properly cold pressed and stored in opaque
containers, is naturally high in phenolic compounds with antioxidant properties,
may be one of the key reasons for the lower incidence of cancer and
cardiovascular disease in the Mediterranean region, suggests a study published
in the British Journal of Nutrition.
This randomized, crossover study involving 10 healthy postmenopausal women in
Florence, Italy, found that when the women consumed extra-virgin olive oil high
in phenols, their DNA experienced a whopping 30% less damage than that seen when
they consumed an olive oil in which the content of phenols, which can be
destroyed by light and heat, was low.
Be sure to buy only cold pressed, extra virgin olive oil sold in an opaque
container or can to prevent its exposure to light and preserve its phenol
content.
Potent Anti-Inflammatory Compound Discovered in Olive Oil
Could olive oil become the new anti-inflammatory standby? Someday soon, your
doctor may recommend you prevent aches and pains, and reduce your risk of
cancer, by telling you to enjoy extra-virgin olive oil with your meals
throughout each day, suggests a study led by Pennsylvania biologist Dr. Gary
Beauchamp and published in Nature.
Inspired by a tasting experience at a molecular gastronomy meeting in Sicily,
where he noticed that high quality olive oil produced a throat-stinging
sensation similar to that caused by ibuprofen, Beauchamp and his team analyzed
freshly pressed extra-virgin olive oil and discovered a compound that suppresses
the prostaglandin system, the same pain pathway as non-steroidal
anti-inflammatory agents, such as ibuprofen.
Although its chemical structure is quite different from the anti-inflammatory
compounds in non-steroidal drugs, olive oil's anti-inflammatory component, which
Beauchamp named "oleocanthal," has a similar effect.
A 50 gram dose (about 4 tablespoons) of extra-virgin olive oil supplies enough
oleocanthal to produce an effect equivalent to that of about 10% of the
ibuprofen dose recommended for adult pain relief.
While this amount won't cure a headache (and most people may not have the room
in their diet for the calories and fat contained in 4 tablespoons of olive oil),
daily consumption of olive oil may prevent inflammation and confer some of the
benefits of long-term ibuprofen use-without the increased risk of intestinal
bleeding and damage to the kidneys that long-term use of non-steroidal drugs
like ibuprofen also carries.
Plus, extra-virgin olive oil can greatly enhance not just your health, but your
enjoyment of your meals throughout the day.
For a really satisfying breakfast, add a tablespoon of olive oil to your
morning frittata.
Dress up your luncheon salad with a second tablespoon and a splash of lemon
juice or balsamic vinegar. Or place your olive oil and vinegar in a small dish
and enjoy as a flavoring for a slice of crusty whole grain bread.
Enhance your dinner vegetables with a sprinkling of grated Parmesan cheese and
a third tablespoon of olive oil, and
Top off your brown rice or pasta.
Scientists believe this finding is significant because inflammation plays a key
role in a variety of chronic diseases. "Some of the health-related effects of
the Mediterranean diet may be due to the activity of oleocanthal from premium
olive oils," said Beauchamp.
Dr Paul Breslin, who directed the research with Beauchamp, added: "The
Mediterranean diet, of which olive oil is a central component, has long been
associated with numerous health benefits, including decreased risk of stroke,
heart disease, breast cancer, lung cancer, and some dementias. Now that we know
of oleocanthal's anti-inflammatory properties, it seems plausible that
oleocanthal plays a causal role in the health benefits associated with diets
where olive oil is the principal source of fat."
Although oleocanthal should be present in any extra-virgin olive oil,
concentrations will vary depending upon a range of factors, including the
variety of olive and the age of the olives at pressing.
The best way to check your olive oil for oleocanthal content? "Sip the oil neat
and see how strongly it stings the back of the throat," recommends Breslin. "The
greater the sting, the greater the oleocanthal content."
Supports Gastrointestinal Health
While most other fats are associated with an increased risk of colon cancer,
olive oil is actually associated with a reduced risk of this disease.
One reason for olive oil's protective effect may be its ability to reduce the
amount of carcinogenic heterocyclic amines (HAs) formed when meats are cooked,
suggests a study published in Food Chemistry Toxicology. The addition of foods
containing antioxidants to recipes containing meat has previously been shown to
decrease the amount of HAs produced during cooking. In this study, beefburgers
were fried in both virgin and refined olive oils as well as virgin olive oil
with rosemary extract and refined olive oil with rosemary extract. Burgers fried
in virgin olive oil had significantly less HAs than those cooked in refined
olive oil; however, the longer the oil was stored, the less its HA-reducing
effect-a good reason to buy olive oil in small quantities that you will use
within a month or two. Researchers theorized that adding rosemary to virgin
olive oil might help prevent this drop in its protective effects.
The incidence of colon cancer is lower in Mediterranean countries compared with
those in northern Europe, a benefit believed to be due to the central role of
olive oil in the Mediterranean diet. Laboratory research published in the
International Journal of Cancer further supports this hypothesis, showing that
phenolic compounds in virgin olive oil protect against several stages of colon
cancer development.
To investigate olive oils' protective mechanisms of action, researchers at the
University of Ulster in Northern Ireland extracted phenols from virgin olive oil
and used them in a series of in vitro (lab test) experiments modeling important
stages of colon carcinogenesis.
In one cell culture experiment, colon cells incubated with olive phenols for 24
hours were protected from hydrogen peroxide-induced DNA damage. The higher the
level of olive oil phenols, the better the protection.
In a second cell culture, at 48 hours, olive phenols at a concentration of 50
μg/ml or more had significantly improved the barrier function of colon
epithelial cells (the cells that form the lining of the colon), suggesting that
the phenols might be exert an anti-promoter effect in the carcinogenesis
pathway.
A third cell culture showed significant inhibition of HT115, a highly invasive
human colorectal cancer cell line, at phenol concentrations of 25, 50, 75 and
100 μg/ml, indicating that olive oil phenols might also reduce the invasiveness
of colon cancer cells.
Olive oil Effective against Helicobacter pylori
Helicobacter pylori, a bacteria that burrows into the gastric lining causing
chronic inflammation and promoting the development of peptic ulcers and gastric
cancer, is becoming increasingly resistant to antibiotics.
The search is on for other substances able to fight H.pylori with researchers
increasingly turning not only to herbal extracts and essential oils used in
traditional medicines, but to polyphenol-rich foods.
Virgin olive oil, one of the few edible oils that is consumed unrefined,
contains a number of active phytonutrients. Having run experiments on food-borne
pathogens that showed olive oil polyphenols have a very high level of
antimicrobial activity against food-borne pathogens, Concepcion Romero and her
colleagues at the University Hospital of Valme, Seville, Spain, decided to in
investigate olive oil's effects on H.pylori.
Using conditions that simulated the human gastric environment, Dr. Romero and
her team demonstrated that a significant amount of the polyphenols in the olive
oil diffused from the oil into the stomach acid and remained stable for several
hours, exerting strong anti-H.pylori activity, even against some strains
resistant to antibiotics.
Also, only very low concentrations of the olive oil extracts were necessary.
Among the polyphenols showing anti-H.pylori activity, one named Ty-EDA was so
effective that only <1.5 μg/mL of this compound was needed to kill H.pylori
cells in test tube experiments. To put this in practical perspective, Ty-EDA is
present in most virgin olive oils in concentrations up to 240 μg/mL.
While these results need confirmation in human studies, they are quite
promising, especially given earlier Russian research involving olive oil and
gastric ulcer. In this study, when patients with gastric and duodenal ulcers
replaced the animal fat in their diet with olive oil, ulcer size was greatly
reduced and the percentage of ulcer healing significantly increased. (Taits NS,
cited in de la Lastra A, et al.,Current Pharmaceutical Design).
Practical Tip: Promote your gastrointestinal health by replacing the butter and
refined oils in your diet with extra virgin olive oil. Since the phenols and
vitamin E in olive oil are damaged by light and heat, purchase and store your
olive oil in an opaque container. And don't use olive oil for cooking. Steam or
lightly sauté foods in a flavorful broth, then dress with olive oil immediately
after cooking. You'll get more flavor and more nutrients from your oil.
A Fat That Can Help You Lose Fat
Substituting olive oil, a monounsaturated fat or MUFA, for saturated fat in your
diet can translate into a small but significant loss of both body weight and fat
mass without changing anything else about your diet or increasing your physical
activity, suggests a study published in the British Journal of Nutrition. One of
the most interesting facts about this research is that it was conducted on eight
overweight or obese men, ranging in age from 24 to 49 years. All the men
followed one of two diets for 4 weeks each. The first, saturated fat-rich diet
provided 24% of calories from saturated fat, 13% from monounsaturated fat, and
3% from polyunsaturated fat, while in the second MUFA-rich diet, 11% of calories
came from saturated fats, 22% from monounsaturated fat and 7% from
polyunsaturated fat. At the end of the MUFA-rich diet, despite the fact that no
significant differences were detected in caloric intake, energy expenditure or
physical activity, the men were 2.1 kg lighter and their fat mass had decreased
by 2.6 kg.
Additional support for olive oil's fat burning effects comes from another study
published in the British Journal of Nutrition, which suggests that the
monounsaturated fats found in olive oil cause an increase in the breakdown of
fats in fat cells (adipocytes). In this study, 45 laboratory animals were
divided into three groups, each of which was fed a diet supplying normal energy
but a different type of fat: olive oil, palmitic acid or soybean oil + palmitic
acid. At the end of the study, a number of indicators of fat metabolism were
measured including body weight, plasma leptin, tissue concentration of fatty
acids, fat-cell size, fat cell lipolytic (fat breakdown) activity, and the
capacity of insulin to inhibit fat breakdown. In the animals receiving
monounsaturated fats, not only was fat breakdown greater, but insulin's ability
to block it was lower. Interestingly, in rats given polyunsaturated fat in the
form of soybean oil, the opposite effect was noted in adipose (fat) tissue.
Extra virgin olive oil is definitely one of the best food oils available today.
Simply adding olive oil to an unhealthy diet that is already soaked in saturated
fats or vegetable oils will not lead to any of the benefits listed above and may
actually cause more harm than good, but when pure, extra virgin olive oil is
used as a primary source of fat in a whole foods, healthy eating plan, the
potential goodness of this oil prevails.
Description
Olive oil is made from the crushing and then subsequent pressing of olives. The
fact that olives are rich in oil is reflected in the botanical name of the olive
tree-Olea europaea-as oleas means oil in Latin.
Olive oil is available in a variety of grades, which reflect the degree to which
it has been processed. See How to Select and Store for more information on these
different grades of olive oil.
History
Olives, one of the oldest foods known, are thought to have originated in Crete
between five and seven thousand years ago. Since ancient times, the olive tree
has provided food, fuel, timber and medicine for many civilizations, and has
been regarded as a symbol of peace and wisdom. The venerable oil of the olive
has been consumed since as early as 3,000 B.C.
Olives were brought to America by the Spanish and Portuguese explorers during
the 15th and 16th centuries. They were introduced into California by the
Franciscan missionaries in the late 18th century. Olive oil has been and still
is a staple in the diet of many Mediterranean countries. The recent discovery
that the Mediterranean diet, which features this prized oil, may be linked to a
reduced risk of heart disease and other health conditions has caused olive oil
to become very popular in the United States in the past few decades. Today, much
of the commercial cultivation of olive oil is still centered in the
Mediterranean region in such countries as Spain, Italy, Greece, Portugal and
Turkey.
How to Select and Store
Since olive oil can become rancid from exposure to light and heat, there are
some important purchasing criteria you should follow to ensure buying a better
quality product. Look for olive oils that are sold in dark tinted bottles since
the packaging will help protect the oil from oxidation caused by exposure to
light. In addition, make sure the oil is displayed in a cool area, away from any
direct or indirect contact with heat.
When you shop for olive oil, you will notice a host of different grades are
available, including extra-virgin, fine virgin, refined and pure.
Extra-virgin is the unrefined oil derived from the first pressing of the
olives and has the most delicate flavor.
Virgin is also derived from the first pressing of the olives but has a higher
acidity level than extra virgin olive oil (as well as less phytonutrients and
a less delicate taste)
Chemically, the difference between extra virgin olive oil and virgin olive oil
involves the amount of free oleic acid, which is a marker for overall acidity.
According to the standards adopted by the International Olive Oil Council,
"virgin" can contain up to 2% free oleic acid, while "extra virgin" can
contain up to 0.8% of free oleic acid.
Pure oil is a bit of a misnomer. Don't be fooled if you see the term "pure" on
the label; it means the oil is a blend of refined and virgin olive oils.
Another term that you may see on a bottle of olive oil is "cold pressed." This
term means that minimal heating was used when mechanically processing the olives
to make oil.
Proper storage techniques for olive oil are very important, not only to preserve
the delicate taste of the oil, but also to ensure that it does not spoil and
become rancid, which will have a negative effect on its nutritional profile.
Even though olive oil's monounsaturated fats are more stable and heat-resistant
than the polyunsaturated fats that predominate in other oils (especially the
easily damaged omega-3 fatty acids found in flax seed oil, which should always
be refrigerated and never heated), olive oil should be stored properly and used
within a few months to ensure its healthy phytonutrients remain intact and
available.
Research conducted at the University of Lleida in Spain and reported in the
Journal of Agriculture and Food Chemistry found that levels of chlorophyll,
carotenoids and antioxidant phenols dropped dramatically after virgin olive oil
had been in storage 12 months-even under the best controlled conditions.
Chlorophyll content dropped by as much as 30%; beta-carotene by 40%, and vitamin
E (alpha-tocopherol) by 100%!
Phenols, which are not only the main antioxidants in virgin olive oil, but are
also responsible for its distinctive rich flavor, also dropped precipitously
after 12 months storage.
Research published in New Scientist magazine has confirmed that light destroys
many of the antioxidants in olive oil. Researchers at the University of Bari, in
southern Italy, compared oils stored in the light or in the dark for 12 months.
Oils stored in clear bottles under supermarket lighting lost at least 30% of
their tocopherols (vitamin E) and carotenoids.
After just two months' exposure to light, peroxide (free radical) levels had
increased so much that the olive oil could no longer be classified as extra
virgin.
Tinted glass containers screen out some light, but non-reactive dark plastic or
metal containers are the best choice for preserving olive oil's beneficial
compounds.
If purchasing oil in tinted glass containers, choose those at the back of the
grocery shelf out of direct light. Unless you are certain turnover is rapid at
your grocery, ask your grocer how long the olive oil has been out on the shelf.
Buy your olive oil in smaller containers and store it in the dark. Leaving a
bottle of olive oil out on your kitchen counter or dining room table will lessen
its health-giving properties.
Be Sure to Choose Extra Virgin (or at least Virgin) Olive Oil
A study published in the European Journal of Nutrition indicates that virgin
olive oil provides significantly greater protection against free radical damage
to LDL cholesterol-one of the first steps in the initiation of atherosclerosis.
In this double-blind, cross-over, randomized clinical trial, 30 healthy
volunteers were given three similar olive oils whose concentration of
antioxidant phenols ranged from 0 to 150 mg/Kg. The three olive oils were each
given for 3 weeks, preceded by a 2-week washout period. After each 3-week phase,
the amount of oxidized (damaged) LDL in volunteers' blood was analyzed, and in
test tube studies, their LDL's ability to resist damage was evaluated. Not only
did consumption of virgin olive oil result in less oxidized LDL, and LDL that
was more damage resistant, but virgin olive oil was also more effective in
raising levels of HDL, the protective form of cholesterol, than the other oils.
The take home message:
Since you phytonutrients are more concentrated in extra virgin olive oil found
in opaque, airtight glass bottles or tins, this is your best bet when purchasing
olive oil for both your taste enjoyment and your health.
Purchase only as much as you will use in three to four months and store away
from light and heat. Protect your olive oil's flavor and antioxidants by
transferring a week to 10 days' worth of oil to a smaller bottle to lessen the
oxidation that occurs when the oil is exposed to air. Leave this small bottle at
room temperature for easy use, but refrigerate the rest. When chilled, olive oil
will solidify slightly and turn cloudy, but once restored to room temperature,
it will regain its normal appearance, and its quality will be better maintained.
Although it may be convenient, definitely don't store your olive oil near the
stove as the heat will damage it.
How to Enjoy
For some of our favorite recipes, click Recipes
A Word About Heating
Different manufacturers list different smoke points for their olive oils, and
some manufacturers list a temperature very close to smoke point as their maximum
limit for safe heating of the oil. When these temperatures might be correct for
avoiding large amounts of some harmful substances that can be created through
heating of the oil, they are not correct limits for preserving the unique
nutrients (especially polyphenols) found in high-quality, extra virgin olive
oil. Oxidation of nourishing substances found in extra virgin olive oil, as well
as acrylamide formation, can occur at cooking temperatures very closer to the
300F range. For these reasons, we recommend a much stricter heating standard
involving very little or no heating when enjoying this delightful oil.
If You're Going to Stir Fry Your Broccoli in Oil, Use Extra Virgin Olive or
Sunflower Oil
Broccoli is known to be a rich source of cancer-preventive glucosinolates,
phenols, vitamin C and minerals (potassium, sodium, calcium, magnesium, iron,
manganese, zinc, and copper). Stir-frying methods that would best maintain
broccoli's rich array of nutrients were investigated by Spanish researchers.
When they stir-fried freshly harvested broccoli florets in various edible oils
(extra virgin olive oil, refined olive oil, sunflower oil, peanut oil, soybean
oil, and safflower oil), they discovered that levels of vitamin C and phenolic
compounds were more affected than those of minerals and glucosinolates. Only
broccoli lightly stir-fried in extra virgin olive oil or sunflower oil retained
the same glucosinolate and vitamin C levels as uncooked broccoli. J Food Sci.
2007 Jan;72(1):S064-8. While we recommend cooking your broccoli by using either
George's healthy sauté method (in which a few tablespoons of broth are used
during cooking instead of oil, and the vegetable dressed with oil immediately
afterwards), or light steaming, if you must use oil, select an organic extra
virgin olive oil or sunflower oil, and be sure to stir fry for the shortest
amount of time.
A Few Quick Serving Ideas:
Use extra virgin olive oil in your salad dressings.
Purée roasted garlic, cooked potatoes and extra virgin olive oil together to
make exceptionally delicious garlic mashed potatoes. Season to taste.
Drizzle extra virgin olive oil over healthy sautéed vegetables before serving.
Purée extra virgin olive oil, garlic and your favorite beans together in a food
processor. Season to taste and serve as a dip.
Instead of putting the butter dish out on the table, place a small cup of extra
virgin olive oil out instead to use on your bread or rolls. For extra flavor,
try adding a little Balsamic vinegar or any of your favorite spices to the extra
virgin olive oil.
Individual Concerns
Olive oil is not a commonly allergenic food and is not known to contain
measurable amounts of goitrogens, oxalates, or purines.
Nutritional Profile
Olive oil is a concentrated source of monounsaturated fats and vitamin E.
Extra-virgin olive oil also contains polyphenolic phytonutrients that have
antioxidant activity.
For an in-depth nutritional profile click here: Olive oil.
In-Depth Nutritional Profile
In addition to the nutrients highlighted in our ratings chart, an in-depth
nutritional profile for Olive oil, extra virgin is also available. This profile
includes information on a full array of nutrients, including carbohydrates,
sugar, soluble and insoluble fiber, sodium, vitamins, minerals, fatty acids,
amino acids and more.
Introduction to Food Rating System Chart
In order to better help you identify foods that feature a high concentration of
nutrients for the calories they contain, we created a Food Rating System. This
system allows us to highlight the foods that are especially rich in particular
nutrients. The following chart shows the nutrients for which this food is either
an excellent, very good, or good source (below the chart you will find a table
that explains these qualifications). If a nutrient is not listed in the chart,
it does not necessarily mean that the food doesn't contain it. It simply means
that the nutrient is not provided in a sufficient amount or concentration to
meet our rating criteria. (To view this food's in-depth nutritional profile that
includes values for dozens of nutrients - not just the ones rated as excellent,
very good, or good - please use the link below the chart.) To read this chart
accurately, you'll need to glance up in the top left corner where you will find
the name of the food and the serving size we used to calculate the food's
nutrient composition. This serving size will tell you how much of the food you
need to eat to obtain the amount of nutrients found in the chart. Now, returning
to the chart itself, you can look next to the nutrient name in order to find the
nutrient amount it offers, the percent Daily Value (DV%) that this amount
represents, the nutrient density that we calculated for this food and nutrient,
and the rating we established in our rating system. For most of our nutrient
ratings, we adopted the government standards for food labeling that are found in
the U.S. Food and Drug Administration's "Reference Values for Nutrition
Labeling." Read more background information and details of our rating system.
Extra Virgin Olive Oil
1.00 tbs
14.00 grams
126.00 calories
NutrientAmountDV
(%)Nutrient
DensityWorld's Healthiest
Foods Rating
World's Healthiest
Foods RatingRule
excellentDV>=75%ORDensity>=7.6ANDDV>=10%
very goodDV>=50%ORDensity>=3.4ANDDV>=5%
goodDV>=25%ORDensity>=1.5ANDDV>=2.5%
In-Depth Nutritional Profile for Olive oil, extra virgin
References
Aguilera CM, Ramirez-Tortosa MC, Mesa MD, Gil A. [Protective effect of
monounsaturated and polyunsaturated fatty acids on the development of
cardiovascular disease]. Nutr Hosp 2001 May-2001 Jun 30;16(3):78-91 2001.
PMID:11620.
Alarcon de la Lastra C, Barranco MD, Motilva V, Herrerias JM. Mediterranean
diet and health: biological importance of olive oil. Curr Pharm Des. 2001
Jul;7(10):933-50. 2001. PMID:11472248.
Beauchamp GK, Keast RS, Morel D, Lin J, Pika J, Han Q, Lee CH, Smith AB,
Breslin PA. Phytochemistry: ibuprofen-like activity in extra-virgin olive oil.
Nature. 2005 Sep 1;437(7055):45-6. 2005. PMID:16136122.
Bond R, Lloyd DH. A double-blind comparison of olive oil and a combination of
evening primrose oil and fish oil in the management of canine atopy. Vet Rec
1992 Dec 12;131(24):558-60 1992. PMID:11330.
Bondia-Pons I, Schroder H, Covas MI, Castellote AI, Kaikkonen J, Poulsen HE,
Gaddi AV, Machowetz A, Kiesewetter H, Lopez-Sabater MC. Moderate consumption
of olive oil by healthy European men reduces systolic blood pressure in
non-Mediterranean participants. J Nutr. 2007 Jan;137(1):84-87. 2007.
PMID:17182805.
Caponio F, Bilancia MT, Pasqualone A, Sikorska E, Gomes T. Influence of the
exposure to light on extra virgin olive oil quality during storage. European
Food Research and Technology, 2005 July; 221(1-2):92-98. 2005.
Carluccio MA, Siculella L, Ancora MA et al. Olive oil and red wine antioxidant
polyphenols inhibit endothelial activation antiatherogenic properties of
mediterranean diet phytochemicals. Arterioscler Thromb Vasc Biol 2003 Apr 1;
23(4):622-9 2003.
Covas MI, de la Torre K, Farre-Albaladejo M, Kaikkonen J, Fito M,
Lopez-Sabater C, Pujadas-Bastardes MA, Joglar J, Weinbrenner T,
Lamuela-Raventos RM, de la Torre R. Postprandial LDL phenolic content and LDL
oxidation are modulated by olive oil phenolic compounds in humans. Free Radic
Biol Med. 2006 Feb 15;40(4):608-16. Epub 2005 Oct 18. 2006. PMID:16458191.
Covas MI, Nyyssonen K, Poulsen HE, Kaikkonen J, Zunft HJ, Kiesewetter H, Gaddi
A, de la Torre R, Mursu J, Baumler H, Nascetti S, Salonen JT, Fito M, Virtanen
J, Marrugat J. EUROLIVE Study Group. The effect of polyphenols in olive oil on
heart disease risk factors: a randomized trial. Ann Intern Med. 2006 Sep
5;145(5):333-41. 2006. PMID:16954359.
Covas MI. Olive oil and the cardiovascular system. Pharmacol Res. 2007
Mar;55(3):175-86. Epub 2007 Jan 30. 2007. PMID:17321749.
Ensminger AH, Esminger M. K. J. e. al. Food for Health: A Nutrition
Encyclopedia. Clovis, California: Pegus Press; 1986 1986. PMID:15210.
Garcia-Segovia P, Sanchez-Villegas A, Doreste J, Santana F, Serra-Majem L.
Olive oil consumption and risk of breast cancer in the Canary Islands: a
population-based case-control study. Public Health Nutr 2006 Feb;9(1A):163-7.
2006. PMID:16512965.
Gill CI, Boyd A, McDermott E, McCann M, Servili M, Selvaggini R, Taticchi A,
Esposto S, Montedoro G, McGlynn H, Rowland I. Potential anti-cancer effects of
virgin olive oil phenols on colorectal carcinogenesis models in vitro. Int J
Cancer. 2005 Oct 20;117(1):1-7. 2005. PMID:15880398.
Haban P, Klvanova J, Zidekova E, Nagyova A. Dietary supplementation with olive
oil leads to improved lipoprotein spectrum and lower n-6 PUFAs in elderly
subjects. Dietary supplementation with olive oil leads to improved lipoprotein
spectrum and lower n-6 PUFAs in elderly subjects. Med Sci Monit. 2004 Mar
23;10(4):PI49-PI54. 2004. PMID:15039655.
Hashim YZ, Eng M, Gill CI, McGlynn H, Rowland IR. Components of olive oil and
chemoprevention of colorectal cancer. Nutr Rev. 2005 Nov;63(11):374-86. 2005.
PMID:16370222.
Hillestrom PR, Covas MI, Poulsen HE. Effect of dietary virgin olive oil on
urinary excretion of etheno-DNA adducts. Free Radic Biol Med. 2006 Oct
1;41(7):1133-8. Epub 2006 Jul 4. 2006. PMID:16962938.
Kontogianni MD, Panagiotakos DB, Chrysohoou C, Pitsavos C, Zampelas A,
Stefanadis C. The impact of olive oil consumption pattern on the risk of acute
coronary syndromes: The CARDIO2000 case-control study. Clin Cardiol. 2007
Mar;30(3):125-9. 2007. PMID:17385704.
Machowetz A, Poulsen HE, Gruendel S, Weimann A, Fito M, Marrugat J, de la
Torre R, Salonen JT, Nyyssonen K, Mursu J, Nascetti S, Gaddi A, Kiesewetter H,
Baumler H, Selmi H, Kaikkonen J, Zunft HJ, Cova. Effect of olive oils on
biomarkers of oxidative DNA stress in Northern and Southern Europeans. FASEB
J. 2007 Jan;21(1):45-52. Epub 2006 Nov 16. 2007. PMID:17110467.
Marrugat J, Covas MI, Fito M, Schroder H, Miro-Casas E, Gimeno E,
Lopez-Sabater MC, De La Torre R, Farre M. Effects of differing phenolic
content in dietary olive oils on lipids and LDL oxidation: A randomized
controlled trial. Eur J Nutr. 2004 Jun;43(3):140-7. 2004. PMID:15168036.
Martinez-Dominguez E, de la Puerta R, Ruiz-Gutierrez V. Protective effects
upon experimental inflammation models of a polyphenol-supplemented virgin
olive oil diet. Inflamm Res 2001 Feb;50(2):102-6 2001. PMID:11630.
Masella R, Vari R, D'Archivio M, Di Benedetto R, Matarrese P, Malorni W,
Scazzocchio B, Giovannini C. Extra Virgin Olive Oil Biophenols Inhibit
Cell-Mediated Oxidation of LDL by Increasing the mRNA Transcription of
Glutathione-Related Enzymes. J Nutr. 2004 Apr;134(4):785-91. 2004.
PMID:15051826.
Masia R, Pena A, Marrugat J, Sala J, Vila J, Pavesi M, Covas M, Aubo C, Elosua
R. High prevalence of cardiovascular risk factors in Gerona, Spain, a province
with low myocardial infarction incidence. REGICOR Investigators. J Epidemiol
Community Health. 1998 Nov;52(11):707-15. 1998. PMID:10396503.
Menendez JA, Vellon L, Colomer R, Lupu R. Oleic acid, the main monounsaturated
fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and
synergistically enhances the growth inhibitory effects of trastuzumab
(HerceptinTM) in breast. Ann Oncol. 2005 Jan 10; [Epub ahead of print] 2005.
PMID:15642702.
Morello JR, Motilva MJ, Tovar MJ, Romero MP. Changes in commercial virgin
olive oil (cv Arbequina) during storage, with special emphasis on the phenolic
fraction. J Agric Food Chem, 2004 May; 85(3):357-364. 2004.
Moreno DA, López-Berenguer C, García-Viguera C. Effects of stir-fry cooking
with different edible oils on the phytochemical composition of broccoli. J
Food Sci. 2007 Jan;72(1):S064-8. 2007. PMID:17995900.
Moreno JJ. Effect of olive oil minor components on oxidative stress and
arachidonic acid mobilization and metabolism by macrophages RAW 264.7. Free
Radic Biol Med. 2003 Nov 1;35(9):1073-81. 2003.
Paniagua JA, Gallego de la Sacristana A, Romero I, Vidal-Puig A, Latre JM,
Sanchez E, Perez-Martinez P, Lopez-Miranda J, Perez-Jimenez F. Monounsaturated
fat-rich diet prevents central body fat distribution and decreases
postprandial adiponectin expression induced by a carbohydrate-rich diet in
insulin-resistant subjects. Diabetes Care. 2007 Jul;30(7):1717-23. Epub 2007
Mar 23. 2007. PMID:17384344.
Persson E, Graziani G, Ferracane R, Fogliano V, Skog K. Influence of
antioxidants in virgin olive oil on the formation of heterocyclic amines in
fried beefburgers. Food Chem Toxicol. 2003 Nov;41(11):1587-97. 2003.
Piers LS, Walker KZ, Stoney RM, Soares MJ, O'Dea K. Substitution of saturated
with monounsaturated fat in a 4-week diet affects body weight and composition
of overweight and obese men. Br J Nutr. 2003 Sep;90(3):717-27 2003.
Psaltopoulou T, Naska A, Orfanos P, Trichopoulos D, Mountokalakis T,
Trichopoulou A. Olive oil, the Mediterranean diet, and arterial blood
pressure: the Greek European Prospective Investigation into Cancer and
Nutrition (EPIC) study. Am J Clin Nutr. 2004 Oct;80(4):1012-8. 2004.
PMID:15447913.
Puel C, Mathey J, Agalias A, Kati-Coulibaly S, Mardon J, Obled C, Davicco MJ,
Lebecque P, Horcajada MN, Skaltsounis AL, Coxam V. Dose-response study of
effect of oleuropein, an olive oil polyphenol, in an ovariectomy/inflammation
experimental model of bone loss in the rat. Clin Nutr. 2006 May 30; [Epub
ahead of print] 2006. PMID:16740345.
Puel C, Quintin A, Agalias A, Mathey J, Obled C, Mazur A, Davicco MJ, Lebecque
P, Skaltsounis AL, Coxam V. Olive oil and its main phenolic micronutrient
(oleuropein) prevent inflammation-induced bone loss in the ovariectomised rat.
Br J Nutr. 2004 Jul;92(1):119-27. 2004. PMID:15230995.
Romero C, Medina E, Vargas J, Brenes M, Castro AD. In Vitro Activity of Olive
Oil Polyphenols against Helicobacter pylori. J Agric Food Chem. 2007 Feb
7;55(3):680-6. 2007. PMID:17263460.
Ruano J, López-Miranda J, de la Torre R, Delgado-Lista J, Fernández J,
Caballero J, Covas MI, Jiménez Y, Pérez-Martínez P, Marín C, Fuentes F,
Pérez-Jiménez F. Intake of phenol-rich virgin olive oil improves the
postprandial prothrombotic profile in hypercholesterolemic patients. Am J Clin
Nutr. 2007 Aug;86(2):341-6. 2007. PMID:17684203.
Ruano J, Lopez-Miranda J, Fuentes F, Moreno JA, Bellido C, Perez-Martinez P,
Lozano A, Gomez P, Jimenez Y, Perez Jimenez F. Phenolic content of virgin
olive oil improves ischemic reactive hyperemia in hypercholesterolemic
patients. J Am Coll Cardiol. 2005 Nov 15;46(10):1864-8. 2005. PMID:16286173.
Salvini S, Sera F, Caruso D, Giovannelli L, Visioli F, Saieva C, Masala G,
Ceroti M, Giovacchini V, Pitozzi V, Galli C, Romani A, Mulinacci N,
Bortolomeazzi R, Dolara P, Palli D. Daily consumption of a high-phenol
extra-virgin olive oil reduces oxidative DNA damage in postmenopausal women.
Br J Nutr. 2006 Apr;95(4):742-51. 2006. PMID:16571154.
Soriguer F, Moreno F, Rojo-Martinez G, Garcia-Fuentes E, Tinahones F,
Gomez-Zumaquero JM, Cuesta-Munoz AL, Cardona F, Morcillo S. Monounsaturated
n-9 fatty acids and adipocyte lipolysis in rats.Br J Nutr. 2003
Dec;90(6):1015-22. 2003.
Valavanidis A, Nisiotou C, Papageorgiou Y, Kremli I, Satravelas N, Zinieris N,
Zygalaki H. Comparison of the Radical Scavenging Potential of Polar and
Lipidic Fractions of Olive Oil and Other Vegetable Oils under Normal
Conditions and after Thermal Treatment.J Agric Food Chem. 2004 Apr
21;52(8):2358-65. 2004. PMID:15080646.
Visioli F, Romani A, Mulinacci N, et al. Antioxidant and other biological
activities of olive mill waste waters. J Agric Food Chem 1999
Aug;47(8):3397-401 1999. PMID:11320.
Weinbrenner T, Fito M, Farre Albaladejo M, Saez GT, et al,. Bioavailability of
phenolic compounds from olive oil and oxidative/antioxidant status at
postprandial state in healthy humans. Drugs Exp Clin Res. 2004;30(5-6):207-12.
2004. PMID:15700748.
Wood, Rebecca. The Whole Foods Encyclopedia. New York, NY: Prentice-Hall
Press; 1988 1988. PMID:15220.
More of the World's Healthiest Foods (& Spices)!
© 2001-2009 The George Mateljan Foundation
Ah, This is perfect! Dispells
ReplyDeletea few misnomers I've been hearing.
Hi it's me, I am also visiting this web page on a regular basis, this website is actually pleasant and the visitors are in fact sharing pleasant thoughts.
ReplyDeleteMy web site - website
Hi there, I found your web site via Google at the same time
ReplyDeleteas looking for a similar topic, your web site came up, it appears to be like good.
I've bookmarked it in my google bookmarks.
Hello there, simply changed into alert to your weblog via Google, and located that it is really informative. I'm going to be careful for brussels.
I'll appreciate in the event you continue this in future. Many other people will be benefited out of your writing. Cheers!
my website: diet program
My brother recommended I might like this website. He used to be totally right.
ReplyDeleteThis post truly made my day. You cann't believe just how so much time I had spent for this info! Thanks!
My page www.Customizedfatlossreviews.info